B-cell leukemia/lymphoma panel is a blood test that looks for certain proteins on the surface of white blood cells called B-lymphocytes. The proteins serve as markers that may be helpful in diagnosing leukemia or lymphoma.
The blood sample is sent to a laboratory, where a specialist checks the cell type and characteristics. This procedure is called immunophenotyping. The test is usually done using a technique called flow cytometry.
How to Prepare for the Test
No special preparation is usually necessary.
How the Test will Feel
When the needle is inserted to draw blood, some persons feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
Why the Test is Performed
This test may be done for the following reasons:
When other tests (such as a blood smear) show signs of abnormal white blood cells
Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.